Francisco Sáez-Orellana

ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons

Francisco Sáez-Orellana, Pamela A. Godoy, Camila Y. Bastidas et al. · Neuropharmacology · 2015 · 52 citations

Synaptic Plasticity, Molecular Neuroscience, Synaptic Signaling +13

Synaptic failure and adenosine triphosphate imbalance induced by amyloid‐β aggregates are prevented by blueberry‐enriched polyphenols extract

Jorge Fuentealba, Andrea J. Dibarrart, María Cecilia Fuentes-Fuentes et al. · Journal of Neuroscience Research · 2011 · 47 citations · Full text

P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease

Francisco Sáez-Orellana, María Cecilia Fuentes-Fuentes, Pamela A. Godoy et al. · Neuropharmacology · 2017 · 43 citations · Full text

Alzheimer's Disease, P2x Receptor Overexpression, Medicine +11

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity

Francisco Sáez-Orellana, Thomas Leroy, Floriane Ribeiro et al. · JCI Insight · 2021 · 36 citations · Full text

Brain Development, Synaptic Transmission, Neurotransmitter +27

Synaptic Silencing and Plasma Membrane Dyshomeostasis Induced by Amyloid-β Peptide are Prevented by Aristotelia chilensis Enriched Extract

Jorge Fuentealba, Andrea J. Dibarrart, Francisco Sáez-Orellana et al. · Journal of Alzheimer s Disease · 2012 · 35 citations · Full text