Christian Fizames

Antitumor imidazotetrazines. 14. Synthesis and antitumor activity of 6- and 8-substituted imidazo[5,1-d]-1,2,3,5-tetrazinones and 8-substituted pyrazolo[5,1-d]-1,2,3,5-tetrazinones

E. Lunt, Christopher G. Newton, Christopher Smith et al. · Journal of Medicinal Chemistry · 1987 · 68 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5

Experimental antitumor activity against murine tumor model systems of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one (mitozolomide), a novel broad-spectrum agent.

John J.A. Hickman, Malcolm F. G. Stevens, P.N. Gibson et al. · PubMed · 1985 · 51 citations

Medicine, Oncology, Pharmacology +12

Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agents

Keith R. Horspool, M. F. G. STEVENS, Christopher G. Newton et al. · Journal of Medicinal Chemistry · 1990 · 42 citations

Medicine, Medicinal Chemistry, Pharmacology +5

Antitumor activity and mechanism of action of the marine compound girodazole

François Lavelle, Aurelio Zerial, Christian Fizames et al. · Investigational New Drugs · 1991 · 29 citations

Natural Sciences, Medicinal Chemistry, Pharmacology +14

Synthesis and antitumor activity of 3′-C-methyl-daunorubicin

Ton That Thang, J.‐L. IMBACH, Christian Fizames et al. · Carbohydrate Research · 1985 · 14 citations

Medicine, Medicinal Chemistry, Oncology +11