P.A. Elkins

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text

Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16

Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Mark A. Seefeld, William H. Miller, Kenneth A. Newlander et al. · Journal of Medicinal Chemistry · 2003 · 161 citations · Full text

Bioorganic Chemistry, Chemical Biology, Pharmaceutical Chemistry +20

Structure of the C-terminally truncated human ProMMP9, a gelatin-binding matrix metalloproteinase

P.A. Elkins, Yen Sen Ho, Ward W. Smith et al. · Acta Crystallographica Section D Biological Crystallography · 2002 · 154 citations

A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1

P.A. Elkins, Amy Bunker, William Cramer et al. · Structure · 1997 · 132 citations · Full text

Microbial Toxin, Crystal Structure, Membrane Formation +9

Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase

P.A. Elkins, Joseph Watts, Magdalena Zalacaín et al. · Journal of Molecular Biology · 2003 · 122 citations

Natural Sciences, Biocatalysis, Molecular Biology +1