Zara J. Franklin

Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection

Luis Fernando Delgadillo-Silva, Anastasia Tsakmaki, Nadeem Akhtar et al. · Disease Models & Mechanisms · 2019 · 35 citations · Full text

Life Sciences, Pharmacology, Physiology +17

Two novel glucagon receptor antagonists prove effective therapeutic agents in high‐fat‐fed and obese diabetic mice

Finbarr O’Harte, Zara J. Franklin, Nigel Irwin · Diabetes Obesity and Metabolism · 2014 · 26 citations

Medicine, Endocrinology, Pharmacology +17

Characterisation of structurally modified analogues of glucagon as potential glucagon receptor antagonists

Finbarr O’Harte, Zara J. Franklin, E.P. Rafferty et al. · Molecular and Cellular Endocrinology · 2013 · 25 citations

Medicine, Medicinal Chemistry, Pharmacology +12

The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice

Ruta Dekeryte, Zara J. Franklin, Claire Hull et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2021 · 19 citations

Medicine, Molecular Medicine, Pharmacology +14

Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice

Laura M. McShane, Zara J. Franklin, Finbarr O’Harte et al. · Peptides · 2014 · 18 citations

Life Sciences, Endocrinology, Pharmacology +17