Isaac Brownell

Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial

Howard L. Kaufman, Jeffery S. Russell, Omid Hamid et al. · The Lancet Oncology · 2016 · 1.2K citations · Full text

Medicine, Metronomic Therapy, Pathology +3

Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

Isaac Brownell, Elizabeth Guevara, Chen Bai et al. · Cell stem cell · 2011 · 453 citations · Full text

Nerve-derived Sonic Hedgehog, Skin Development, Cell Lineage +10

The Abscopal Effect Associated With a Systemic Anti-melanoma Immune Response

Emily F. Stamell, Jedd D. Wolchok, Sacha Gnjatic et al. · International Journal of Radiation Oncology*Biology*Physics · 2013 · 377 citations · Full text

Inflammation, Immune Evasion, Cancer Immunosurveillance +10

Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial

Howard L. Kaufman, Jeffery S. Russell, Omid Hamid et al. · Journal for ImmunoTherapy of Cancer · 2018 · 323 citations · Full text

Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial

Sandra P. D’Angelo, Shailender Bhatia, Andrew S. Brohl et al. · Journal for ImmunoTherapy of Cancer · 2020 · 193 citations · Full text