Prema Iyer

Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism

Qingqiu Huang, Clint A. Stalnecker, Chengliang Zhang et al. · Journal of Biological Chemistry · 2018 · 87 citations · Full text

Design and evaluation of novel glutaminase inhibitors

Lee McDermott, Prema Iyer, Shawn Rimer et al. · Bioorganic & Medicinal Chemistry · 2016 · 72 citations · Full text

Medicine, Rational Drug Design, Pharmacotherapy +4

Design and activity of AP endonuclease-1 inhibitors

Zhiwei Feng, Stanton J. Kochanek, David A. Close et al. · Journal of Chemical Biology · 2015 · 31 citations · Full text

Medicine, Ap Endonuclease-1 Inhibitors, Drug Development +3

Mutagenicity of N3-methyladenine: A multi-translesion polymerase affair

Paola Monti, Ilaria Traverso, Laura Casolari et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2009 · 28 citations

Multi-translesion Polymerase Affair, Natural Sciences, Molecular Biology +4

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

Fen Pei, Hongchun Li, Mark J. Henderson et al. · Scientific Reports · 2017 · 22 citations · Full text