Jimmy B. Payappilly

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

Renee Haskew-Layton, Jimmy B. Payappilly, N. A. Smirnova et al. · Proceedings of the National Academy of Sciences · 2010 · 151 citations · Full text

Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration

Sama F. Sleiman, Brett Langley, Manuela Basso et al. · Journal of Neuroscience · 2011 · 140 citations · Full text

Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators

N. A. Smirnova, Renee Haskew-Layton, Manuela Basso et al. · Chemistry & Biology · 2011 · 100 citations

Real-time Monitoring, Biochemistry, High Throughput Screening +5

Utilization of an In Vivo Reporter for High Throughput Identification of Branched Small Molecule Regulators of Hypoxic Adaptation

N. A. Smirnova, Ilay Rakhman, Natalia Moroz et al. · Chemistry & Biology · 2010 · 74 citations · Full text

Hypoxic Adaptation, Signal Transduction, Biochemistry +12

15‐Deoxy‐Δ12,14‐prostaglandin J2 (15d‐<scp>PGJ</scp>2) protects neurons from oxidative death via an Nrf2 astrocyte‐specific mechanism independent of <scp>PPAR</scp>γ

Renee Haskew-Layton, Jimmy B. Payappilly, Hongbin Xu et al. · Journal of Neurochemistry · 2012 · 33 citations · Full text

Nrf2 Astrocyte‐specific Mechanism, Lipid Peroxidation, Cell Death +22