Heyu Chen

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

Mi Deng, Xun Gui, Jaehyup Kim et al. · Nature · 2018 · 284 citations · Full text

Cancer Immunosurveillance, T Cell Suppression, Immunology +9

A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML

Samuel John, Heyu Chen, Mi Deng et al. · Molecular Therapy · 2018 · 137 citations · Full text

LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells

Zunling Li, Mi Deng, Fangfang Huang et al. · Cellular and Molecular Immunology · 2019 · 81 citations · Full text

T Cell Suppression, Immunology, Hematology +6

LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis

Guojin Wu, Yixiang Xu, Robbie D. Schultz et al. · Nature Cancer · 2021 · 79 citations · Full text

Cancer Immunosurveillance, Traf2–cflip–nf-κb Signaling Axis, Immune Cell Development +13

Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells

Heyu Chen, Yuanzhi Chen, Mi Deng et al. · Journal for ImmunoTherapy of Cancer · 2020 · 59 citations · Full text