Karl R. Gibson

Remote, 1,5-anti stereoinduction in the boron-mediated aldol reactions of β-oxygenated methyl ketones

Ian Paterson, Karl R. Gibson, Renata M. Oballa · Tetrahedron Letters · 1996 · 157 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Rapid Discovery of a Novel Series of Abl Kinase Inhibitors by Application of an Integrated Microfluidic Synthesis and Screening Platform

Bimbisar Desai, Karen Dixon, Elizabeth Farrant et al. · Journal of Medicinal Chemistry · 2013 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral Fellowship to T.T.), NSERC-Canada (Postdoctoral Fellowship to R.M.O.), Churchill College (Research Fellowship to D.J.W.), Kingapos;s College and Sims Fund, Cambridge (Scholarship to D.Y.K.C.). We also thank Merck and AstraZeneca Pharmaceuticals for generous support, and Dr. Anne Butlin (AZ) and Dr. Nick Bampos (Cambridge) for valuable assistance.

Ian Paterson, David Y.‐K. Chen, Mark J. Coster et al. · Angewandte Chemie International Edition · 2001 · 116 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain

S. Skerratt, Mark D. Andrews, Sharan K. Bagal et al. · Journal of Medicinal Chemistry · 2016 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity

Charles E. Mowbray, Stéphanie Braillard, William C. Speed et al. · Journal of Medicinal Chemistry · 2015 · 67 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16