Mark J. Coster

Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II

Lan‐Feng Dong, Victoria J.A. Jameson, David Tilly et al. · Journal of Biological Chemistry · 2010 · 202 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral Fellowship to T.T.), NSERC-Canada (Postdoctoral Fellowship to R.M.O.), Churchill College (Research Fellowship to D.J.W.), Kingapos;s College and Sims Fund, Cambridge (Scholarship to D.Y.K.C.). We also thank Merck and AstraZeneca Pharmaceuticals for generous support, and Dr. Anne Butlin (AZ) and Dr. Nick Bampos (Cambridge) for valuable assistance.

Ian Paterson, David Y.‐K. Chen, Mark J. Coster et al. · Angewandte Chemie International Edition · 2001 · 116 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

Lan‐Feng Dong, Victoria J.A. Jameson, David Tilly et al. · Free Radical Biology and Medicine · 2011 · 105 citations · Full text

Life Sciences, Cell Biology, Oncology +17

A Concise Route to Dihydrobenzo[<i>b</i>]furans: Formal Total Synthesis of (+)-Lithospermic Acid

J Fischer, G. Paul Savage, Mark J. Coster · Organic Letters · 2011 · 62 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment

Ian Paterson, Mark J. Coster, David Y.‐K. Chen et al. · Organic & Biomolecular Chemistry · 2005 · 51 citations

Pharmacy, Chemistry, Medicinal Chemistry +15