Marie D. Ralff

Role of Dopamine Receptors in the Anticancer Activity of ONC201

C. Leah B. Kline, Marie D. Ralff, Amriti R. Lulla et al. · Neoplasia · 2017 · 121 citations · Full text

Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212

Jessica Wagner, C. Leah B. Kline, Marie D. Ralff et al. · Cell Cycle · 2017 · 79 citations · Full text

Chemoprevention Strategy, Imipridone Family, Tumor Biology +17

Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment

Jessica Wagner, C. Leah B. Kline, Lanlan Zhou et al. · Journal of Clinical Investigation · 2018 · 78 citations · Full text

ONC201 Demonstrates Antitumor Effects in Both Triple-Negative and Non–Triple-Negative Breast Cancers through TRAIL-Dependent and TRAIL-Independent Mechanisms

Marie D. Ralff, C. Leah B. Kline, Ozan C. Küçükkase et al. · Molecular Cancer Therapeutics · 2017 · 57 citations

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

Avital Lev, Amriti R. Lulla, Jessica Wagner et al. · Oncotarget · 2017 · 48 citations · Full text