Isaac Downs

NLRC5/MHC class I transactivator is a target for immune evasion in cancer

Sayuri Yoshihama, Jason Roszik, Isaac Downs et al. · Proceedings of the National Academy of Sciences · 2016 · 264 citations · Full text

Regional and disease specific human lung extracellular matrix composition

Evan T. Hoffman, Franziska E. Uhl, Loredana Asarian et al. · Biomaterials · 2022 · 48 citations · Full text

Inflammatory Lung Disease, Advanced Lung Disease, Lung Inflammation +8

The ROS Scavenger, NAC, Regulates Hepatic Vα14iNKT Cells Signaling during Fas mAb-Dependent Fulminant Liver Failure

Isaac Downs, Jianfeng Liu, Tak Yee Aw et al. · PLoS ONE · 2012 · 39 citations · Full text

Apoptosis, Immunology, Immune Regulation +31

Vα14iNKT cell deficiency prevents acetaminophen-induced acute liver failure by enhancing hepatic glutathione and altering APAP metabolism

Isaac Downs, Tak Yee Aw, Jianfeng Liu et al. · Biochemical and Biophysical Research Communications · 2012 · 24 citations · Full text

Hepatology, Allergy, Medicine +12

Natural History of Aerosol Induced Lassa Fever in Non-Human Primates

Isaac Downs, Carl Shaia, Xiankun Zeng et al. · Viruses · 2020 · 20 citations · Full text