Characterization of Blackberry Extract and Its Antiproliferative and Anti-Inflammatory Properties

Jin Dai, Jigna D. Patel, Russell J. Mumper

Journal of Medicinal Food

Discovery of a Clinical Candidate from the Structurally Unique Dioxa-bicyclo[3.2.1]octane Class of Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Vincent Mascitti, Tristan S. Maurer, Ralph P. Robinson, +24

Journal of Medicinal Chemistry

Pharmaceutical ScienceClinical CandidatePharmacotherapyChemical BiologyPharmaceutical Chemistry +14

Preparation and Characterization of Nickel Nanoparticles for Binding to His-tag Proteins and Antigens

Jigna D. Patel, Ronan O’Carra, Julia A. Jones, +2

Pharmaceutical Research

NanoparticlesEngineeringBiochemistryNanomaterialsNanotechnology +6

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

Samit K. Bhattacharya, Kim Andrews, Ramsay E. Beveridge, +25

ACS Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryG Protein-coupled ReceptorMedicine +8

Strong T cell type-1 immune responses to HIV-1 Tat (1–72) protein-coated nanoparticles

Zhengrong Cui, Jigna D. Patel, Marina Tuzova, +4

Vaccine

MedicineProtein-coated NanoparticlesHuman RetrovirusImmunologyAntiviral Response +9

C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization

Ralph P. Robinson, Vincent Mascitti, Carine M. Boustany‐Kari, +18

Bioorganic & Medicinal Chemistry Letters

C-5 SpirocyclizationSugar ModificationsMedicinal ChemistryBiochemistryMedicine +10

Ezetimibe (Zetia): A New Type of Lipid-Lowering Agent

Jigna D. Patel, Valerie Sheehan, Cheryle Gurk‐Turner

Baylor University Medical Center Proceedings

Lipid-lowering AgentCardiometabolic RiskHyperlipidemiaCholesterol SynthesisMetabolic Syndrome +18

Peripheral administration of poly I:C leads to increased hippocampal amyloid-beta and cognitive deficits in a non-transgenic mouse

Marielle Kahn Weintraub, Dinko Kranjac, Micah J. Eimerbrink, +7

Behavioural Brain Research

Peripheral AdministrationAlzheimer's DiseaseDegenerative PathologyNeurochemical BiomarkersCognitive Deficits +6

HIV-1 Tat-coated nanoparticles result in enhanced humoral immune responses and neutralizing antibodies compared to alum adjuvant

Jigna D. Patel, David Galey, Jeffrey M. Jones, +4

Vaccine

NanomedicineHiv-1 Tat-coated NanoparticlesHuman RetrovirusImmunologyAntiviral Response +7

Evaluation and Synthesis of Polar Aryl- and Heteroaryl Spiroazetidine-Piperidine Acetamides as Ghrelin Inverse Agonists

Suvi T. M. Orr, Ramsay E. Beveridge, Samit K. Bhattacharya, +20

ACS Medicinal Chemistry Letters

Piperidine AmidesPharmacotherapyHeterocycle ChemistryPharmaceutical ChemistryGhrelin Inverse Agonists +15