Itziar Otano

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

Álvaro Teijeira, Saray Garasa, María Gato et al. · Immunity · 2020 · 718 citations · Full text

Inflammation, Cytokine, Immune Cytotoxicity +8

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Elísabeth Pérez-Ruiz, Luna Minute, Itziar Otano et al. · Nature · 2019 · 465 citations · Full text

Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host

Anna Schurich, Laura J. Pallett, Danyal Jajbhay et al. · Cell Reports · 2016 · 247 citations · Full text

Adaptive Immune System, Human Retrovirus, Distinct Metabolic Requirements +10

Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy

Sarita M. Fernández‐Poma, Diego Salas‐Benito, Teresa Lozano et al. · Cancer Research · 2017 · 136 citations

Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells

Iñaki Etxeberría, Elixabet Bolaños, José I. Quetglas et al. · Cancer Cell · 2019 · 132 citations · Full text

Cell Therapy, Il-12 Mrna, Cancer Immunosurveillance +7