Joseph D. Fullerton

Solubility-Driven Optimization of Phosphodiesterase-4 Inhibitors Leading to a Clinical Candidate

Neil J. Press, Roger Taylor, Joseph D. Fullerton et al. · Journal of Medicinal Chemistry · 2012 · 33 citations · Full text

Medicinal Chemistry, Solubility-driven Optimization, Pharmaceutical Science +13

Design and Synthesis of Thrombin Inhibitors:  Analogues of MD-805 with Reduced Stereogenicity and Improved Potency

Derek E. Brundish, Alice Bull, Vera Donovan et al. · Journal of Medicinal Chemistry · 1999 · 29 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Thrombin Inhibitors +15

Reactivity and structure of N-phenylnaphth-1-ylamines and related compounds. Part 1. Reactions with alkylperoxyl radicals

John E. Bennett, G. Brunton, Alexander R. Forrester et al. · Journal of the Chemical Society Perkin Transactions 2 · 1983 · 21 citations

Engineering, Peroxyl Radical, Photochemistry +13

Discovery and Optimization of 4-(8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl)transcyclohexanecarboxylic Acid, an Improved PDE4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease (COPD)

Neil J. Press, Roger Taylor, Joseph D. Fullerton et al. · Journal of Medicinal Chemistry · 2015 · 18 citations · Full text

Pde4 Inhibitors, Medicinal Chemistry, Compound 2 +14

Nitroxide radicals. Part 21. Spontaneous decomposition of N-aryl 1- and 2-naphthyl nitroxides

Alexander R. Forrester, Joseph D. Fullerton, Gordon McConnachie · Journal of the Chemical Society Perkin Transactions 1 · 1983 · 18 citations

Engineering, Biochemistry, Reactive Nitrogen Specie +13