Oscar R. Diago

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

Timothy F. Cloughesy, Joseph Landolfi, Daniel J. Hogan et al. · Science Translational Medicine · 2016 · 196 citations

Oncologic Imaging, Pathology, Recurrent High-grade Glioma +19

Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

Timothy F. Cloughesy, Joseph Landolfi, Michael A. Vogelbaum et al. · Neuro-Oncology · 2018 · 174 citations · Full text

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

Omar D. Perez, Christopher R. Logg, Kei Hiraoka et al. · Molecular Therapy · 2012 · 137 citations · Full text

Intravenous Administration of Retroviral Replicating Vector, Toca 511, Demonstrates Therapeutic Efficacy in Orthotopic Immune-Competent Mouse Glioma Model

Tiffany Huang, Shraddha Parab, Ryan Burnett et al. · Human Gene Therapy · 2014 · 64 citations · Full text

Intravenous Administration, Immunology, Immunoediting +16

Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

Chris Twitty, Oscar R. Diago, Daniel J. Hogan et al. · Human Gene Therapy Methods · 2015 · 36 citations · Full text

Immunology, Breast Cancer Tissue, Cancer Biology +16