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Publication | Open Access

Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

DOIFull Paper Access

174

Citations

38

References

2018

Year

Timothy F. Cloughesy, Joseph Landolfi, Michael A. Vogelbaum, Derek Ostertag, J. Bradley Elder, Stephen M. Bloomfield, Bob S. Carter, Clark C. Chen, Steven N. Kalkanis, Santosh Kesari,
Neuro-Oncology

Abstract

Multiyear durable responses have been observed in rHGG patients treated with Toca 511 + Toca FC in a phase I trial, and the treatment will be further evaluated in a randomized phase III trial. Among IDH1 mutant patients treated at first recurrence, there may be an enrichment of complete responders.

References

YearCitations

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