Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

Karin Steinbach, Ilena Vincenti, Mario Kreutzfeldt, +7

The Journal of Experimental Medicine

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

Giovanni Di Liberto, Stanislav Pantelyushin, Mario Kreutzfeldt, +19

Cell

MedicineT-regulatory CellImmunologyAutoimmunityT Cell Immunity +3

Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells

Nicolas Pagé, Bogna Klimek, Mathias De Roo, +16

Immunity

Dna-binding Factor ToxEncephalitogenic PotentialAutoimmune DiseaseT-regulatory CellImmunology +7

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice

Karin Steinbach, Ilena Vincenti, Kristóf Égervári, +14

Science Translational Medicine

Tissue-resident memory CD8 ⁺ T cells cooperate with CD4 ⁺ T cells to drive compartmentalized immunopathology in the CNS

Ilena Vincenti, Nicolas Pagé, Karin Steinbach, +20

Science Translational Medicine

Cold exposure protects from neuroinflammation through immunologic reprogramming

Martina Spiljar, Karin Steinbach, Dorothée Rigo, +17

Cell Metabolism

Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein

Soheila Emamzadah, Laurence Tropia, Ilena Vincenti, +2

Journal of Molecular Biology

ChromatinGenome InstabilityExtended ConformationProtein AssemblyStructural Bioinformatics +13

Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling

Nicolas Pagé, Sylvain Lemeille, Ilena Vincenti, +6

Nature Communications

Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack

Weldy V. Bonilla, Nicole Kirchhammer, Anna‐Friederike Marx, +17

Cell Reports Medicine

Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity

Danielle Shlesinger, Kai‐Lin Hong, Ghazal Shammas, +22

Genes and Immunity