Jordi Castro

Discovery of Novel Quaternary Ammonium Derivatives of (3<i>R</i>)-Quinuclidinol Esters as Potent and Long-Acting Muscarinic Antagonists with Potential for Minimal Systemic Exposure after Inhaled Administration: Identification of (3<i>R</i>)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane Bromide (Aclidinium Bromide)

María Prat, Dolors Fernández, María Antonia Buil et al. · Journal of Medicinal Chemistry · 2009 · 70 citations · Full text

Biphenyl Pyridazinone Derivatives as Inhaled PDE4 Inhibitors: Structural Biology and Structure–Activity Relationships

Jordi Gràcia, María Antonia Buil, Jordi Castro et al. · Journal of Medicinal Chemistry · 2016 · 25 citations · Full text

Asthma, Inflammatory Lung Disease, Adenosine Receptors +18

Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists

María Prat, María Antonia Buil, Maria Dolors Fernández et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 20 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +8

Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of pyrrolopiperidinone acetic acids as CRTh2 antagonists

Míriam Andrés, María Antonia Buil, Marta Calbet et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 19 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +12

Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists

María Antonia Buil, Marta Calbet, Marcos Castillo et al. · European Journal of Medicinal Chemistry · 2016 · 18 citations · Full text

Combinatorial Chemistry, Sulphone-based Crth2 Antagonists, Biochemistry +8