Jordi Gràcia

Synthesis and biological evaluation of 2,5-dihydropyrazolo[4,3-c]quinolin-3-ones, a novel series of PDE 4 inhibitors with low emetic potential and antiasthmatic properties

M. Crespo, Jordi Gràcia, Carles Puig et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 34 citations · Full text

Medicinal Chemistry, Biochemistry, Low Emetic Potential +8

Novel Pyrazolopyrimidopyridazinones with Potent and Selective Phosphodiesterase 5 (PDE5) Inhibitory Activity as Potential Agents for Treatment of Erectile Dysfunction

Maria Paola Giovannoni, Claudia Vergelli, Claudio Biancalani et al. · Journal of Medicinal Chemistry · 2006 · 34 citations · Full text

Medicinal Chemistry, Compound 5R, Erectile Dysfunction +13

Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases

Montse Erra, Joan Taltavull, Francisco Javier Valera Bernal et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Asthma, Pharmaceutical Science, Inflammatory Lung Disease +19

Synthesis and Biological Activity of Pyrido[3′,2′:4,5]thieno[3,2-<i>d</i>]pyrimidines as Phosphodiesterase Type 4 Inhibitors

Joan Taltavull, Jordi Serrat, Jordi Gràcia et al. · Journal of Medicinal Chemistry · 2010 · 31 citations · Full text

Discovery of a Potent, Selective, and Orally Available PI3Kδ Inhibitor for the Treatment of Inflammatory Diseases

Montse Erra, Joan Taltavull, Angelique Gréco et al. · ACS Medicinal Chemistry Letters · 2016 · 27 citations · Full text

Immunology, Pharmacotherapy, Pharmaceutical Chemistry +18