Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

Nikolaos A. Patsopoulos, Sergio E. Baranzini, Adam Santaniello, +130

Science

ImmunologyExtended MhcInnate ImmunityImmune SystemImmune-related Gene Polymorphism +14

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Marta Olah, Vilas Menon, Naomi Habib, +24

Nature Communications

A transcriptomic atlas of aged human microglia

Marta Olah, Ellis Patrick, Alexandra–Chloé Villani, +17

Nature Communications

Transcriptomic AtlasNeurodegenerative DiseasesGlobal Human PopulationAlzheimer's DiseaseAging +13

Identification of a microglia phenotype supportive of remyelination

Marta Olah, Sandra Amor, Nieske Brouwer, +4

Glia

Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain

Divya Raj, Zhuoran Yin, Marjolein Breur, +10

Frontiers in Molecular Neuroscience

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants

Katie J. Ryan, Charles C. White, K R Patel, +16

Science Translational Medicine

Neurodegenerative DiseasesGenetic VariantsAlzheimer's DiseaseMedicineDegenerative Pathology +9

Priming of microglia in a DNA-repair deficient model of accelerated aging

Divya Raj, Dick Jaarsma, Inge R. Holtman, +15

Neurobiology of Aging

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

NA Patsopoulos, Sergio E. Baranzini, Adam Santaniello, +181

Resident MicrogliaInnate Immune SystemImmunologyInnate ImmunityImmune System +18

Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia

Kirusanthy Kaneshwaran, Marta Olah, Shinya Tasaki, +7

Science Advances

Sleep DisordersAgingImmunologyAlzheimer ’Sleep Fragmentation +18

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

Sarah C. Starossom, Juliana Campo Garcia, Tim Woelfle, +14

Nature Communications

ImmunologyCell DeathChitinase-like ProteinsNeuroinflammationInflammation +17