Deepak Nagrath

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

Hongyun Zhao, Lifeng Yang, Joelle Baddour et al. · eLife · 2016 · 902 citations · Full text

Biological Microenvironments, Extracellular Microvesicles, Metabolic Remodeling +17

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung et al. · Cell Metabolism · 2016 · 429 citations · Full text

Oncogenic Agent, Medicine, Cancer Growth +8

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

Lifeng Yang, Tyler J. Moss, Lingegowda S. Mangala et al. · Molecular Systems Biology · 2014 · 334 citations · Full text

Metabolic Shifts, Biochemistry, Oncogenic Agent +9

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

Prasenjit Dey, Joelle Baddour, Florian L. Müller et al. · Nature · 2017 · 262 citations · Full text

Genomic Deletion, Tumor Biology, Pancreatic Cancer +9

Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel

Kai Han, Jutaek Nam, Jin Xu et al. · Nature Biomedical Engineering · 2021 · 238 citations · Full text

Inflammation, Dysbiosis, Allergy +12