Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy

Xiaoqi Sun, Yu Zhang, Jiaqian Li, +10

Nature Nanotechnology

Sting ActivationBioactive MetalCyclic Dinucleotide–manganese ParticlesMetalloproteinImmunology +5

Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery

Shisong Han, Ze‐Yong Li, Jingyi Zhu, +8

Small

Dual‐Stage‐Light‐Guided Tumor Inhibition by Mitochondria‐Targeted Photodynamic Therapy

Kai Han, Qi Lei, Shibo Wang, +6

Advanced Functional Materials

NanotherapeuticsPhotobiologyRedox BiologyOxidative StressNanomedicine +15

Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel

Kai Han, Jutaek Nam, Jin Xu, +10

Nature Biomedical Engineering

InflammationDysbiosisAllergySystemic Antitumour ImmunityMucosal Immunology +10

Ratiometric Biosensor for Aggregation-Induced Emission-Guided Precise Photodynamic Therapy

Kai Han, Shibo Wang, Qi Lei, +2

ACS Nano

EngineeringPhotochemistryMmp-2-triggered Aie FluorescencePhotodynamic TherapyBiomedical Imaging +8

Acidity‐Triggered Tumor‐Targeted Chimeric Peptide for Enhanced Intra‐Nuclear Photodynamic Therapy

Kai Han, Weiyun Zhang, Jin Zhang, +5

Advanced Functional Materials

Nuclear MedicineEngineeringPhotodynamic TherapyPeptide TherapeuticPoor Tumor Selectivity +7

Tumor-Triggered Geometrical Shape Switch of Chimeric Peptide for Enhanced <i>in Vivo</i> Tumor Internalization and Photodynamic Therapy

Kai Han, Jin Zhang, Weiyun Zhang, +5

ACS Nano

NanomedicineEngineeringPolymer-drug ConjugatePhotodynamic TherapyGeometrical Shape +13

A Tumor Targeted Chimeric Peptide for Synergistic Endosomal Escape and Therapy by Dual‐Stage Light Manipulation

Kai Han, Qi Lei, Huizhen Jia, +5

Advanced Functional Materials

EngineeringPhotobiologyPeptide EngineeringMolecular BiologyPeptide Science +20

Synergistic gene and drug tumor therapy using a chimeric peptide

Kai Han, Si Chen, Wei‐Hai Chen, +4

Biomaterials

MedicinePeptide EngineeringPeptide LibraryPeptide TherapeuticTumor Targeting +6

Dual stimuli-responsive multi-drug delivery system for the individually controlled release of anti-cancer drugs

Wang Xiao, Xuan Zeng, Hang Lin, +3

Chemical Communications

EngineeringBiomedical EngineeringSite-specific DeliveryNanomedicineDrug Delivery System +15