Justin A. MacDonald

Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis

Brian D. Gulbransen, Mohammad Bashashati, Simon A. Hirota et al. · Nature Medicine · 2012 · 436 citations

Inflammation, Mucosal Immunology, Enteric Neurons +7

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Simon A. Hirota, Jeffrey Ng, Alan Lueng et al. · Inflammatory Bowel Diseases · 2010 · 427 citations · Full text

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

Philip Kitchen, Mootaz M. Salman, Andrea Halsey et al. · Cell · 2020 · 416 citations · Full text

Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

Jeffrey Ng, Simon A. Hirota, Yàn Li et al. · Gastroenterology · 2010 · 252 citations

Inflammation, Intestinal Injury Are, Microbial Toxin +11

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

Leanne Mortimer, France Moreau, Justin A. MacDonald et al. · Nature Immunology · 2016 · 244 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +12