Maria S. Brown

Modulation of Glutamine Synthetase Adenylylation and Deadenylylation Is Mediated by Metabolic Transformation of the P _II -Regulatory Protein

Maria S. Brown, Anthony W. Segal, Earl R. Stadtman · Proceedings of the National Academy of Sciences · 1971 · 147 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Late-Stage Microsomal Oxidation Reduces Drug–Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189

Antonia F. Stepan, Tuan P. Tran, Christopher J. Helal et al. · ACS Medicinal Chemistry Letters · 2018 · 38 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Metabolite regulation of the state of adenylylation of glutamine synthetase

Amiel Segal, Maria S. Brown, Earl R. Stadtman · Archives of Biochemistry and Biophysics · 1974 · 37 citations

Life Sciences, Biochemistry, Molecular Biology +10

Biosynthetic studies of ascomycin (FK520): formation of the (1R,3R,4R)-3,4-dihydroxycyclohexanecarboxylic acid-derived moiety

Kimberlee K. Wallace, Kevin A. Reynolds, Kevin Koch et al. · Journal of the American Chemical Society · 1994 · 33 citations

Natural Sciences, Chemistry, Pharmacology +8

Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H ₁ Receptor Inverse Agonist

Manjinder S. Lall, Asser Bassyouni, James Bradow et al. · Journal of Medicinal Chemistry · 2020 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17