Jun Asami

(1<i>S</i>)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-<scp>d</scp>-glucitol (TS-071) is a Potent, Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for Type 2 Diabetes Treatment

Hiroyuki Kakinuma, Takahiro Oi, Yuko Hashimoto-Tsuchiya et al. · Journal of Medicinal Chemistry · 2010 · 154 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Diabetes Management +13

Molecular Characterization of Mammalian Dicarbonyl/l-Xylulose Reductase and Its Localization in Kidney

Junichi Nakagawa, Syuhei Ishikura, Jun Asami et al. · Journal of Biological Chemistry · 2002 · 99 citations · Full text

TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity

Koji Yamamoto, Shusaku Uchida, Kiyokazu Kitano et al. · British Journal of Pharmacology · 2011 · 66 citations · Full text

<i>Suppression of Renal α‐Dicarbonyl Compounds Generated following Ureteral Obstruction by Kidney‐Specific α‐Dicarbonyl/<scp>l</scp>‐Xylulose Reductase</i>

Hiroko Odani, Jun Asami, Aiko Ishii et al. · Annals of the New York Academy of Sciences · 2008 · 13 citations

Renal Inflammation, Ureteral Obstruction, Renal α‐Dicarbonyl Compounds +19

Transgenic Mice Over-expressing Dicarbonyl/L-xylulose Reductase Gene Crossed with KK-Ay Diabetic Model Mice: An Animal Model for the Metabolism of Renal Carbonyl Compounds

Takako Sudo, Aiko Ishii, Jun Asami et al. · EXPERIMENTAL ANIMALS · 2005 · 13 citations · Full text