Joshua P. Plotnik

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert et al. · Nature · 2020 · 389 citations

Bd2 Bromodomain, Medicine, Natural Sciences +9

ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells

Joshua P. Plotnik, Justin A. Budka, Mary W. Ferris et al. · Nucleic Acids Research · 2014 · 120 citations · Full text

Ras/erk Pathway, Tumor Biology, Transcriptional Regulation +17

An Interaction with Ewing’s Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer

Vivekananda Kedage, Nagarathinam Selvaraj, Taylor R. Nicholas et al. · Cell Reports · 2016 · 52 citations · Full text

Specific Oncogenic Mechanism, Radiation Oncology, Ets Factors Rearranged +13

ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase

Sunil Tomar, Joshua P. Plotnik, James Haley et al. · Cancer Letters · 2017 · 50 citations · Full text

Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia

Lu Zhang, Tianyu Cai, Xiaoli Huang et al. · Molecular Cancer Therapeutics · 2021 · 33 citations · Full text