Ovarian cancer progression is controlled by phenotypic changes in dendritic cells

Uciane K. Scarlett, Melanie R. Rutkowski, Adam M. Rauwerdink, +9

The Journal of Experimental Medicine

ImmunologyImmunoeditingGynecologyOvarian Cancer ProgressionImmunotherapy +20

Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity

Juan R. Cubillos‐Ruiz, Xavier Engle, Uciane K. Scarlett, +10

Journal of Clinical Investigation

ImmunologyImmunoeditingImmunotherapeuticsImmunotherapyTumor Biology +15

Reprogramming Tumor-Associated Dendritic Cells <i>In Vivo</i> Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer

Juan R. Cubillos‐Ruiz, Jason R. Baird, Amelia J. Tesone, +9

Cancer Research

<i>In situ</i> Stimulation of CD40 and Toll-like Receptor 3 Transforms Ovarian Cancer–Infiltrating Dendritic Cells from Immunosuppressive to Immunostimulatory Cells

Uciane K. Scarlett, Juan R. Cubillos‐Ruiz, Yolanda C. Nesbeth, +5

Cancer Research

Immune-Mediated Regression of Established B16F10 Melanoma by Intratumoral Injection of Attenuated <i>Toxoplasma gondii</i> Protects against Rechallenge

Jason R. Baird, Katelyn T. Byrne, Patrick H. Lizotte, +10

The Journal of Immunology

Avirulent <i>Toxoplasma gondii</i> Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment

Jason R. Baird, Barbara A. Fox, Kiah L. Sanders, +7

Cancer Research

Depletion of Dendritic Cells Delays Ovarian Cancer Progression by Boosting Antitumor Immunity

Eduardo Huarte, Juan R. Cubillos‐Ruiz, Yolanda C. Nesbeth, +9

Cancer Research

Cancer ImmunosurveillanceTumor Growth RestrictionMedicineTumor GrowthImmunology +12

CD4+ T Cells Elicit Host Immune Responses to MHC Class II− Ovarian Cancer through CCL5 Secretion and CD40-Mediated Licensing of Dendritic Cells

Yolanda C. Nesbeth, Diana G. Martinez, Seiko Toraya, +4

The Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyImmunoediting +22

CD277 is a Negative Co-stimulatory Molecule Universally Expressed by Ovarian Cancer Microenvironmental Cells

Juan R. Cubillos‐Ruiz, Diana G. Martinez, Uciane K. Scarlett, +4

Oncotarget

CCL5-Mediated Endogenous Antitumor Immunity Elicited by Adoptively Transferred Lymphocytes and Dendritic Cell Depletion

Yolanda C. Nesbeth, Uciane K. Scarlett, Juan R. Cubillos‐Ruiz, +4

Cancer Research

ImmunologyDendritic Cell DepletionImmunoeditingImmunologic MechanismImmune Cell Therapy +15