L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

Roger Geiger, Jan C. Rieckmann, Tobias Wolf, +10

Cell

Metabolic modulation of tumours with engineered bacteria for immunotherapy

Fernando P. Canale, Camilla Basso, Gaia Antonini, +13

Nature

Cancer ImmunosurveillanceEngineered BacteriaMedicineImmunologySynthetic Biology +4

Social network architecture of human immune cells unveiled by quantitative proteomics

Jan C. Rieckmann, Roger Geiger, Daniel Hornburg, +8

Nature Immunology

Quantitative ProteomicsEngineeringMedicineBiological NetworkComputational Biology +10

Dynamics in protein translation sustaining T cell preparedness

Tobias Wolf, Wenjie Jin, Giada Zoppi, +16

Nature Immunology

Protein FoldingNatural SciencesProtein BiosynthesisProtein TranslationProtein Engineering +6

Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

Kevin M. Tharp, Kelly Kersten, Ori Maller, +14

Nature Cancer

Tumor-associated MacrophagesCancer ImmunosurveillanceBreast Cancer MicroenvironmentMedicineImmunology +9

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

Anna Kabanova, Jessica Marcandalli, Tongqing Zhou, +16

Nature Microbiology

Molecular VirologyMedicinePathogenesisViral PathogenesisImmunology +5

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

Joshua Tan, Kathrin Pieper, Luca Piccoli, +18

Nature

Malaria Variant AntigensAutoimmune DiseaseMalariaPathogenesisImmunology +8

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

Roger Geiger, Daniel Andritschke, Sarah Friebe, +4

Nature Cell Biology

Natural SciencesSecretory PathwayMolecular BiologyCell DeathProtein Transport +7

Bulk Flow Revisited: Transport of a Soluble Protein in the Secretory Pathway

Friederike Thor, Matthias Gautschi, Roger Geiger, +1

Traffic

Protein SecretionMolecular BiologyCytoskeletonCellular PhysiologyBulk Fluid Flow +15

Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy

Adrià-Arnau Martí i Líndez, Isabelle Dunand-Sauthier, Mark Conti, +12

JCI Insight