Johannes A. M. Christiaans

A Cyclopent-2-enecarbonyl Group Mimics Proline at the P2 Position of Prolyl Oligopeptidase Inhibitors

Elina M. Jarho, Jarkko I. Venäläinen, Juhani Huuskonen et al. · Journal of Medicinal Chemistry · 2004 · 69 citations · Full text

Excellent Proline Mimetic, Chemical Biology, Pharmaceutical Chemistry +16

Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors

Jarkko I. Venäläinen, J. Arturo García‐Horsman, Markus Forsberg et al. · Biochemical Pharmacology · 2006 · 69 citations

Biochemistry, Medicine, Glycobiology +6

Cardiovascular hybrid drugs: combination of more than one pharmacological property in one single molecule

Johannes A. M. Christiaans, H. Timmerman · European Journal of Pharmaceutical Sciences · 1996 · 59 citations

Pharmacological Study, Medicine, Cardiovascular Pharmacology +8

4-Phenylbutanoyl-2(S)-acylpyrrolidines and 4-phenylbutanoyl-l-prolyl-2(S)-acylpyrrolidines as prolyl oligopeptidase inhibitors

Erik A. A. Wallén, Johannes A. M. Christiaans, Susanna M. Saario et al. · Bioorganic & Medicinal Chemistry · 2002 · 36 citations

Dicarboxylic Acid<i>bis</i>(<scp>l</scp>-Prolyl-pyrrolidine) Amides as Prolyl Oligopeptidase Inhibitors

Erik A. A. Wallén, Johannes A. M. Christiaans, Markus Forsberg et al. · Journal of Medicinal Chemistry · 2002 · 35 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Bioorganic Chemistry +15