Coronavirus Main Proteinase (3CL ^pro ) Structure: Basis for Design of Anti-SARS Drugs

K. Anand, John Ziebuhr, Parvesh Wadhwani, +2

Science

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

Haitao Yang, Maojun Yang, Yi Ding, +12

Proceedings of the National Academy of Sciences

Viral ReplicationSars VirusProtein AssemblyBiomolecular Structure PredictionSars-cov Main Protease +15

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

K. Anand

The EMBO Journal

Virus StructureChymotrypsin FoldMolecular VirologyBiochemistryProtein Folding +7

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

Kenji Maeda, K. Anand, Antonella Chiapparino, +4

Nature

Signal TransductionInteractome Map UncoversBiochemistryNatural SciencesMolecular Biology +5

pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (Mpro) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses

Jinzhi Tan, Koen H. G. Verschueren, K. Anand, +11

Journal of Molecular Biology

Ph-dependent Conformational FlexibilityProtein AssemblyBiomolecular Structure PredictionProtein FoldingNatural Sciences +10

The structure and substrate specificity of human Cdk12/Cyclin K

Christian A. Bösken, Lucas Farnung, Corinna Hintermair, +7

Nature Communications

Crystal StructureProtein FunctionSignal TransductionActive Cdk12/cyckSignaling Pathway +10

Structural and Functional Analysis of the Cdk13/Cyclin K Complex

Ann Katrin Greifenberg, Dana Hönig, Květa Pilařová, +6

Cell Reports

Crystal StructureMolecular RegulationMolecular BiologyCdk13/cyclin K ComplexCell Cycle +17

Synthesis and biological evaluation of 2-trifluoromethyl/sulfonamido-5,6-diaryl substituted imidazo[2,1-b]-1,3,4-thiadiazoles: A novel class of cyclooxygenase-2 inhibitors

Andanappa K. Gadad, Mahesh B. Palkar, K. Anand, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryHeterocyclicBiochemistryMedicineNatural Sciences +9

Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV

K. Anand, Antje Schulte, Karin Vogel‐Bachmayr, +2

Nature Structural & Molecular Biology

Transcriptional RegulationNatural SciencesRna BiologyMolecular BiologyGene Expression +4

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains

Ivana Vonkova, Antoine‐Emmanuel Saliba, Samy Deghou, +11

Cell Reports