Concepedia

Author

P De Isabella

Fondazione IRCCS Istituto Nazionale dei Tumori

Also Known As

P De Isabella, P. De Isabella, Paola De Isabella

10

Publications

383

Citations

10

H-Index

21

Concepts

All Affiliations

Fondazione IRCCS Istituto Nazionale dei Tumori
PD

About

P De Isabella is an author at Fondazione IRCCS Istituto Nazionale dei Tumori specializing in pharmacology, medicine, and drug resistance.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

115

2

Health Sciences

1

1

83

3

Natural Sciences

1

1

18

4

Biochemistry

1

1

18

5

Cell Biology

1

1

14

P De Isabella

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10

Publications

383

Citations

10

H-Index

YearCitations

A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.

Paola Perego, Michelandrea De Cesare, P De Isabella,

PubMed

2001

83

Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives.

P De Isabella, Manlio Palumbo, Claudia Sissi,

Molecular Pharmacology

1995

59

Similar sequence specificity of mitoxantrone and VM-26 stimulation of in vitro DNA cleavage by mammalian DNA topoisomerase II

Giovanni Capranico, P De Isabella, Stella Tinelli,

Biochemistry

1993

59

Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells.

P De Isabella, Giovanni Capranico, Monica Binaschi,

Molecular Pharmacology

1990

46

Base sequence determinants of amonafide stimulation of topoisomerase II DNA clevage

P De Isabella, Franco Zunino, Giovanni Capranico

Nucleic Acids Research

1995

40

Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects.

P De Isabella, Giovanni Capranico, Manlio Palumbo,

Molecular Pharmacology

1993

34

Characterization of a Topoisomerase II Gene Rearrangement in a Human Small-Cell Lung Cancer Cell Line

Monica Binaschi, G. Giaccone, Adi F. Gazdar,

JNCI Journal of the National Cancer Institute

1992

19

Physicochemical properties, cytotoxic activity and topoisomerase ii inhibition of 2,3-diaza-anthracenediones

P De Isabella, Manlio Palumbo, Claudia Sissi,

Biochemical Pharmacology

1997

18

P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines

Giovanni Capranico, P De Isabella, Chiara Castelli,

British Journal of Cancer

1989

14

Relationships among tumor responsiveness, cell sensitivity, doxorubicin cellular pharmacokinetics and drug‐induced DNA alterations in two human small‐cell lung cancer xenografts

Graziella Pratesi, Giovanni Capranico, Monica Binaschi,

International Journal of Cancer

1990

11

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