Honglei Chen

Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial

Neeta Somaiah, Anthony P. Conley, Edwin R. Parra et al. · The Lancet Oncology · 2022 · 157 citations

Medicine, Oncology, Pharmacology +16

Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1

Chenlong Wang, Yaxin Chen, Yang Wang et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 108 citations · Full text

Medicine, Oncology, Pharmacology +16

Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6

Haixia Zhao, Xinhua Zhang, Xuewei Chen et al. · Toxicology and Applied Pharmacology · 2014 · 97 citations

Life Sciences, Cancer Biology, Immunology +14

Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis

Miao Qiu, Keqing Huang, Yanzhuo Liu et al. · Mucosal Immunology · 2019 · 94 citations · Full text

Medicine, Cancer Biology, Nutritional Sciences +12

Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

Xianda Zhao, Wei Fan, Zhigao Xu et al. · Oncotarget · 2016 · 92 citations · Full text

Medicine, Oncology, Pharmacology +17