Thomas L Platt

Bridging Integrator 1 (BIN1) Protein Expression Increases in the Alzheimer's Disease Brain and Correlates with Neurofibrillary Tangle Pathology

Christopher J. Holler, Paulina R. Davis, Tina L. Beckett et al. · Journal of Alzheimer s Disease · 2014 · 147 citations · Full text

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

Susan A. Farr, Jessica L. Ripley, Rukhsana Sultana et al. · Free Radical Biology and Medicine · 2013 · 127 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +11

Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease

Thomas L Platt, Tina L. Beckett, Katharina Köhler et al. · Neuroscience · 2015 · 89 citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +10

Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia

Dana M. Niedowicz, Valerie L. Reeves, Thomas L Platt et al. · Acta Neuropathologica Communications · 2014 · 83 citations · Full text

Leptin regulates amyloid β production via the γ-secretase complex

Dana M. Niedowicz, Christa M. Studzinski, Adam M. Weidner et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2012 · 50 citations · Full text

Neurodegenerative Diseases, Protein Secretion, Molecular Physiology +5