Christopher J. Holler

FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage

Qiudong Deng, Christopher J. Holler, Geraldine Taylor et al. · Journal of Neuroscience · 2014 · 167 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Bridging Integrator 1 (BIN1) Protein Expression Increases in the Alzheimer's Disease Brain and Correlates with Neurofibrillary Tangle Pathology

Christopher J. Holler, Paulina R. Davis, Tina L. Beckett et al. · Journal of Alzheimer s Disease · 2014 · 161 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +16

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by<i>GRN</i>Mutations

Christopher J. Holler, Georgia Taylor, Qiudong Deng et al. · eNeuro · 2017 · 137 citations · Full text

Life Sciences, Neurology, Neuroscience +17

BACE1 and BACE2 enzymatic activities in Alzheimer’s disease

Rachel R. Ahmed, Christopher J. Holler, Robin L. Webb et al. · Journal of Neurochemistry · 2009 · 126 citations · Full text

Life Sciences, Biochemistry, Neuroscience +14

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

Christopher J. Holler, Georgia Taylor, Zachary T. McEachin et al. · Molecular Neurodegeneration · 2016 · 108 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17