Spontaneous tumorigenesis in mice defective in the <i>MTH1</i> gene encoding 8-oxo-dGTPase

Teruhisa Tsuzuki, Akinori Egashira, Hisato Igarashi, +12

Proceedings of the National Academy of Sciences

Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts

Keizo Ohnaka, Mizuho Tanabe, Hisaya Kawate, +2

Biochemical and Biophysical Research Communications

Bone Morphogenic ProteinBone RepairOsteoarthritisBone MetabolismCanonical Wnt Signal +5

Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis

Keizo Ohnaka, Hiroshi Taniguchi, Hisaya Kawate, +2

Biochemical and Biophysical Research Communications

InflammationNovel MechanismOrthopaedic SurgeryGlucocorticoid-induced OsteoporosisHuman Osteoblasts +10

Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes

Hisaya Kawate, Kunihiko Sakumi, Teruhisa Tsuzuki, +6

Proceedings of the National Academy of Sciences

ACCELERATED PAPER: Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent

Teruhisa Tsuzuki, Kunihiko Sakumi, Akiko Shiraishi, +11

Carcinogenesis

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyEnzyme O +14

A Single Highly Mutable Catalytic Site Amino Acid Is Critical for DNA Polymerase Fidelity

Premal H. Patel, Hisaya Kawate, Elinor T. Adman, +2

Journal of Biological Chemistry

The Lack of the C-Terminal Domain of Adipose Triglyceride Lipase Causes Neutral Lipid Storage Disease through Impaired Interactions with Lipid Droplets

Kunihisa Kobayashi, Toyoshi Inoguchi, Yasutaka Maeda, +11

The Journal of Clinical Endocrinology & Metabolism

Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes

Akinori Egashira, K. Yamauchi, Kaoru Yoshiyama, +6

DNA repair

Knockout MouseGenome InstabilityDevelopmental BiologyMsh2 GenesSomatic Variant +5

New diagnostic criteria of adrenal subclinical Cushing’s syndrome: opinion from the Japan Endocrine Society

Toshihiko Yanase, Yutaka Oki, Takuyuki Katabami, +8

Endocrine Journal

Inverse associations of serum bilirubin with high sensitivity C-reactive protein, glycated hemoglobin, and prevalence of type 2 diabetes in middle-aged and elderly Japanese men and women

Keizo Ohnaka, Suminori Kono, Toyoshi Inoguchi, +5

Diabetes Research and Clinical Practice

Metabolic SyndromeDiabetes EpidemiologyCardiovascular DiseaseSerum BilirubinDiabetes +6