Ji Nie

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

Wenshuai Li, Xu Zhang, Xingyu Lu et al. · Cell Research · 2017 · 375 citations · Full text

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease

Raffaella Nativio, Yemin Lan, Greg Donahue et al. · Nature Genetics · 2020 · 354 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +11

Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma

Jiabin Cai, Lei Chen, Zhou Zhang et al. · Gut · 2019 · 280 citations · Full text

A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation

Xiaolong Cui, Ji Nie, Jeremy Ku et al. · Nature Communications · 2020 · 213 citations · Full text

A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations

Dali Han, Xingyu Lu, Alan H. Shih et al. · Molecular Cell · 2016 · 177 citations · Full text

Bioinformatics, Robust Method, Single Cell Sequencing +14