BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Uğur Şahin, Alexander Muik, Isabel Vogler, +46

Nature

VaccinationBnt162b2 Vaccine InducesAllergyImmunologyTherapeutic Vaccine +7

BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans

Uğur Şahin, Alexander Muik, Isabel Vogler, +46

Humoral ResponseImmunologyImmunodominanceT CellsCovid-19 +15

Evaluation of SNPs in<i>miR-146a</i>,<i>miR196a2</i>and<i>miR-499</i>as low-penetrance alleles in German and Italian familial breast cancer cases

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Human Mutation

GeneticsLow-penetrance AllelesGenetic EpidemiologyHuman PolymorphismPathology +15

VPA response in SMA is suppressed by the fatty acid translocase CD36

Lutz Garbes, Ludwig Heesen, Irmgard Hölker, +10

Human Molecular Genetics

Epigenetic ChangeMolecular BiologyVpa ResponseEpigeneticsMolecular Signaling +14

Plastin 3 is upregulated in iPSC-derived motoneurons from asymptomatic SMN1-deleted individuals

Ludwig Heesen, Michael Peitz, Laura Torres‐Benito, +15

Cellular and Molecular Life Sciences

Cellular NeurobiologyDevelopmental BiologyMolecular NeuroscienceNeural Stem CellCytoskeleton +7

The influence of different illumination parameters on protoporphyrin IX induced cell death in squamous cell carcinoma cells

B. Novak, Ludwig Heesen, Nicole Schary, +1

Photodiagnosis and Photodynamic Therapy

Abstract CT156: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for immunotherapy of malignant melanoma

Robert A. Jabulowsky, Carmen Loquai, Heidrun Mitzel-Rink, +33

Cancer Research

NanotherapeuticsEngineeringAbstract Ct156Tumor Antigen-encoding RnasImmunology +25

A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for potent melanoma immunotherapy

Ludwig Heesen, Robert A. Jabulowsky, Carmen Loquai, +17

Annals of Oncology

Abstract OT2-06-01: Highly innovative personalized RNA-immunotherapy for patients with triple negative breast cancer

M Schmidt, Stefanie Bolte, Katrin Frenzel, +13

Cancer Research

Breast OncologyImmunologyImmunotherapeuticsImmunotherapyMolecular Therapies +16