Fátima Ortega

Discovery of a Potent and Specific <i>M. tuberculosis</i> Leucyl-tRNA Synthetase Inhibitor: (<i>S</i>)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[<i>c</i>][1,2]oxaborol-1(3<i>H</i>)-ol (GSK656)

Xianfeng Li, Vincent Hernandez, Fernando Rock et al. · Journal of Medicinal Chemistry · 2017 · 162 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection

Giovanna Poce, Robert H. Bates, Salvatore Alfonso et al. · PLoS ONE · 2013 · 94 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor

María Martínez-Hoyos, Esther Pérez‐Herrán, Gülçin Gülten et al. · EBioMedicine · 2016 · 81 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Rosario Díaz-González, Sandra A. Luengo-Arratta, João Seixas et al. · PLoS neglected tropical diseases · 2014 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Antimycobacterial Activity

Uday S. Ganapathy, Rubén González del Río, Mónica Cacho-Izquierdo et al. · Antimicrobial Agents and Chemotherapy · 2021 · 41 citations · Full text

Medicine, Infectious Diseases, Pharmacology +5