Rachel V. K. Cochrane

Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent

Rachel V. K. Cochrane, Randy Sanichar, Gareth R. Lambkin et al. · Angewandte Chemie International Edition · 2015 · 50 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +16

Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism

Shehrazade Jekhmane, Maik G. N. Derks, Sourav Maity et al. · Nature Microbiology · 2024 · 40 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Natural products and their derivatives as tRNA synthetase inhibitors and antimicrobial agents

Rachel V. K. Cochrane, Amy K. Norquay, John C. Vederas · MedChemComm · 2016 · 24 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Comparison of 10,11‐Dehydrocurvularin Polyketide Synthases from <i>Alternaria cinerariae</i> and <i>Aspergillus terreus</i> Highlights Key Structural Motifs

Rachel V. K. Cochrane, Zhizeng Gao, Gareth R. Lambkin et al. · ChemBioChem · 2015 · 17 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

From plant to probe: semi-synthesis of labelled undecaprenol analogues allows rapid access to probes for antibiotic targets

Rachel V. K. Cochrane, Francesca M. Alexander, Coilín Boland et al. · Chemical Communications · 2020 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10