Nicholas J. Porter

Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

Yang Hai, Stephen A. Shinsky, Nicholas J. Porter et al. · Nature Communications · 2017 · 194 citations · Full text

Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors

Nicholas J. Porter, Adaickapillai Mahendran, Ronald Breslow et al. · Proceedings of the National Academy of Sciences · 2017 · 176 citations · Full text

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity

Nicholas J. Porter, J.D. Osko, Daniela Diedrich et al. · Journal of Medicinal Chemistry · 2018 · 103 citations · Full text

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Katharina Vögerl, Nghia Ong, Johanna Senger et al. · Journal of Medicinal Chemistry · 2019 · 98 citations · Full text

Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8

Nicholas J. Porter, David W. Christianson · ACS Chemical Biology · 2017 · 72 citations · Full text