<i>PARK2</i> deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in <i>Apc</i> mutant mice

George Poulogiannis, Rebecca E. McIntyre, Maria Dimitriadi, +8

Proceedings of the National Academy of Sciences

Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis

Anna Kaczmarek, Svenja Schneider, Kathryn J. Swoboda, +24

The American Journal of Human Genetics

NeuroregenerationSpinal Cord InjuryPhysiologyDegenerative DiseaseSpinal Muscular Atrophy +7

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation

Amit Gupta, Sara Anjomani‐Virmouni, Nikos Koundouros, +12

Molecular Cell

Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects

Maria Dimitriadi, James N. Sleigh, Amy K. Walker, +11

PLoS Genetics

GeneticsGenomic MechanismGene CharacterizationMolecular GeneticsDisease Gene Identification +18

C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins

Edward Anderson, Mark E. Corkins, Jia-Cheng Li, +8

Mechanisms of Ageing and Development

Lifespan ExtensionDevelopmental BiologyOsmotic StressLongevityCellular Senescence +5

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

Christopher J. Tape, Stephanie Ling, Maria Dimitriadi, +8

Cell

Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration

Saba Baskoylu, Jill Yersak, Patrick O’Hern, +8

PLoS Genetics

Neurodegenerative DiseasesSingle Copy/knock-in ModelsAmyotrophic Lateral SclerosisMedicineGenetics +11

Decreased function of survival motor neuron protein impairs endocytic pathways

Maria Dimitriadi, Aaron Derdowski, Geetika Kalloo, +10

Proceedings of the National Academy of Sciences

The Neuroprotective Drug Riluzole Acts via Small Conductance Ca²⁺-Activated K⁺Channels to Ameliorate Defects in Spinal Muscular Atrophy Models

Maria Dimitriadi, Min Jeong Kye, Geetika Kalloo, +3

Journal of Neuroscience

Motor Neuron DiseaseSynaptic TransmissionPeripheral NervesCellular NeurobiologySynaptic Signaling +19

The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein

Deborah Y. Kwon, Maria Dimitriadi, Barbara Terzic, +5

Molecular Biology of the Cell

Molecular BiologyCytoskeletonSocial SciencesE3 Ubiquitin LigaseAutophagy +14