Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

Kouetsu Ogasawara, Shigeaki Hida, Nazli Azimi, +6

Nature

Host ResponseHuman CellNatural Killer CellsInnate Immune SystemImmunology +4

Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

Yutaka Tagaya, Gloria Kurys, Tiffany A. Thies, +5

Proceedings of the National Academy of Sciences

Short Signal PeptideImmunologyImmune RegulationNonsecretable Interleukin 15Immunologic Mechanism +18

The 5′ Untranslated Region, Signal Peptide, and the Coding Sequence of the Carboxyl Terminus of IL-15 Participate in Its Multifaceted Translational Control

Richard N. Bamford, Andrew P. DeFilippis, Nazli Azimi, +2

The Journal of Immunology

Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-κB site

Nazli Azimi, Keith Brown, Richard N. Bamford, +3

Proceedings of the National Academy of Sciences

Adaptive Immune SystemT-regulatory CellImmunologyImmune RegulationImmunodominance +21

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

Gustavo Baldassarre, Monica Fedele, Sabrina Battista, +7

Proceedings of the National Academy of Sciences

Human T Cell Lymphotropic Virus Type I Tax Activates IL-15Rα Gene Expression Through an NF-κB Site

Jennifer Mariner, Valerie Lantz, Thomas A. Waldmann, +1

The Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmunologyPathologyImmunologic Mechanism +18

Transcriptional Up-Regulation of the Cyclin D2 Gene and Acquisition of New Cyclin-Dependent Kinase Partners in Human T-Cell Leukemia Virus Type 1-Infected Cells

Francisco Santiago, Elizabeth Clark, Siewyen Chong, +6

Journal of Virology

Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor.

Nazli Azimi, Steven Jacobson, Thomas Leist, +1

PubMed

Il-2/15r Beta ReceptorImmunodeficienciesImmunologyImmune RegulationPathology +15

Involvement of IL-15 in the Pathogenesis of Human T Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis: Implications for Therapy with a Monoclonal Antibody Directed to the IL-2/15Rβ Receptor

Nazli Azimi, Steven Jacobson, Thomas Leist, +1

The Journal of Immunology

Clinical ImmunologyImmunodeficienciesImmune RegulationImmunologyImmunodominance +22

Overexpression of p21 ^waf1 in Human T-Cell Lymphotropic Virus Type 1-Infected Cells and Its Association with Cyclin A/cdk2

Cynthia de la Fuente, Francisco Santiago, Siew Yen Chong, +9

Journal of Virology