Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

Massimo Donadelli, Ilaria Dando, Tatyana Zaniboni, +10

Cell Death and Disease

Hyaluronic acid-coated liposomes for active targeting of gemcitabine

Silvia Arpicco, Carlotta Lerda, Elisa Dalla Pozza, +8

European Journal of Pharmaceutics and Biopharmaceutics

NanomedicineHyaluronic Acid-coated LiposomesEngineeringNano-drug DeliveryBiomedical Engineering +3

Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells

Ilaria Dando, Massimo Donadelli, C. Costanzo, +4

Cell Death and Disease

MitophagyKrebs CycleAmpk-dependent AutophagyMetabolic RemodelingPancreatic Cancer Cells +14

Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition

Marco Cordani, Elisa Oppici, Ilaria Dando, +11

Molecular Oncology

Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways

Jessica Brandi, Ilaria Dando, Elisa Dalla Pozza, +10

Journal of Proteomics

Lineage PlasticityPancreatic CancerMedicineMevalonate PathwaysFunctional Role +9

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

Ilaria Dando, Claudia Fiorini, Elisa Dalla Pozza, +4

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Pancreatic Adenocarcinoma CellsSignal TransductionPancreatic CancerCell RegulationMedicine +8

Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine

Elisa Dalla Pozza, Claudia Fiorini, Ilaria Dando, +5

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Mitochondrial FunctionMedicineNatural SciencesCancer Cell ResistanceMolecular Biology +5

Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity

Elisa Dalla Pozza, Carlotta Lerda, Chiara Costanzo, +9

Biochimica et Biophysica Acta (BBA) - Biomembranes

Antitumoral ActivityPancreatic Adenocarcinoma CellsDrug TargetingPancreatic CancerMedicine +7

The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition

Jessica Brandi, Daniela Cecconi, Marco Cordani, +10

Free Radical Biology and Medicine

Pancreatic CancerPkm2 ExpressionBiochemistryMedicinePancreas Cancer Cells +5

Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes

Alessandro Marengo, Stefania Forciniti, Ilaria Dando, +9

Biochimica et Biophysica Acta (BBA) - General Subjects

Tumor BiologyPancreatic CancerHealth SciencesHyaluronic AcidMedicine +10