Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice

Yasushi Yabuki, Yasushi Ohizumi, Akihito Yokosuka, +2

Neuroscience

Nobiletin TreatmentNeuropharmacologyCognitive DeficitsNeuroprotectionNeuroscience +4

Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome

Norifumi Shioda, Yasushi Yabuki, K Yamaguchi, +9

Nature Medicine

Gene TherapiesGenetic DisorderNatural SciencesGeneticsFragile X Spectrum +6

FABP3 Protein Promotes α-Synuclein Oligomerization Associated with 1-Methyl-1,2,3,6-tetrahydropiridine-induced Neurotoxicity

Norifumi Shioda, Yasushi Yabuki, Yuka Kobayashi, +3

Journal of Biological Chemistry

CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome

Sefan Asamitsu, Yasushi Yabuki, Susumu Ikenoshita, +12

Science Advances

Reduced calcium/calmodulin‐dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP‐treated mice

Shigeki Moriguchi, Yasushi Yabuki, Kohji Fukunaga

Journal of Neurochemistry

Brain FunctionSynaptic TransmissionNeurotransmitterNeurotransmissionMptp Treatment +20

Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice

Shigeki Moriguchi, Hiroyuki Sakagami, Yasushi Yabuki, +5

Molecular Neurobiology

PsychoneuroimmunologyPsychiatryBehavioral NeuroscienceMedicineMood Symptom +10

Oral administration of glutathione improves memory deficits following transient brain ischemia by reducing brain oxidative stress

Yasushi Yabuki, Kohji Fukunaga

Neuroscience

Transient Brain IschemiaBrain Oxidative StressMemory DeficitsMedicineDementia +10

trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway

Yusuke Hirata, Miki Takahashi, Yuki Kudoh, +9

Journal of Biological Chemistry

InflammationBiochemistryProinflammatory SignalingOmega-3 Fatty AcidApoptosis +9

Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism

Yun Tian, Yasushi Yabuki, Shigeki Moriguchi, +12

Journal of Pineal Research

Autism Spectrum DisordersSynaptic TransmissionSynaptic SignalingSocial SciencesNeurodiversity +19

RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons

Sefan Asamitsu, Yasushi Yabuki, Kazuya Matsuo, +8

Science Advances

Dnaptp6 Phase SeparationMolecular NeuroscienceNatural SciencesRna Structure PredictionRna Biology +11