Hengjiang Guo

Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy

Aili Cao, Li Wang, Xia Chen et al. · Laboratory Investigation · 2016 · 119 citations

Renal Function, Biochemistry, Medicine +11

Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKα-regulated autophagy induction in streptozotocin-induced diabetic nephropathy

Hengjiang Guo, Yi Wang, Xuemei Zhang et al. · Scientific Reports · 2017 · 100 citations · Full text

Klotho ameliorates diabetic nephropathy by activating Nrf2 signaling pathway in podocytes

Lina Xing, Hengjiang Guo, Sixuan Meng et al. · Biochemical and Biophysical Research Communications · 2020 · 84 citations · Full text

Cell Death, Nrf2 Signaling, Redox Biology +21

Astragaloside IV attenuates podocyte apoptosis through ameliorating mitochondrial dysfunction by up-regulated Nrf2-ARE/TFAM signaling in diabetic kidney disease

Qian Shen, Ji Fang, Hengjiang Guo et al. · Free Radical Biology and Medicine · 2023 · 83 citations · Full text

Mitochondrial Dysfunction, Apoptosis, Cell Death +20

Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax

Jingyao Li, Xiang Dong Sun, Ninghao Yang et al. · Kidney International · 2022 · 76 citations

Inflammation, Biochemistry, Mitochondrial Function +11