Genomewide Search for Type 2 Diabetes–Susceptibility Genes in French Whites: Evidence for a Novel Susceptibility Locus for Early-Onset Diabetes on Chromosome 3q27-qter and Independent Replication of a Type 2–Diabetes Locus on Chromosome 1q21–q24

Nathalie Vionnet, El Habib Hani, S. Dupont, +10

The American Journal of Human Genetics

Genome-wide Association StudyGenetic DeterminantGenotype-phenotype AssociationGeneticsGenetic Epidemiology +9

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

El Habib Hani, Doris A. Stoffers, Jean-Claude Chèvre, +5

Journal of Clinical Investigation

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

Gérard Waeber, Jérôme Delplanque, Christophe Bonny, +13

Nature Genetics

Gene Mapk8ip1GeneticsDiabetesType 2Islet Cell Manufacturing +4

Cloning, Functional Expression, and Chromosomal Localization of the Human Pancreatic Islet Glucose-Dependent Insulinotropic Polypeptide Receptor

Sandrine Gremlich, Andrée Porret, El Habib Hani, +4

Diabetes

Mutation screening in 18 Caucasian families suggest the existence of other MODY genes

Jean-Claude Chèvre, El Habib Hani, Philippe Boutin, +12

Diabetologia

BiologyGenetic AnalysisAllelic VariantGenetic TestingGenetic Disorder +8

A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus.

El Habib Hani, Laurence Suaud, Philippe Boutin, +10

Journal of Clinical Investigation

GeneticsGenetic EpidemiologyPathologyMolecular GeneticsDisease Gene Identification +17

Extracellularly Regulated Kinases 1/2 (p44/42 Mitogen-Activated Protein Kinases) Phosphorylate Synapsin I and Regulate Insulin Secretion in the MIN6 β-Cell Line and Islets of Langerhans

Christine Longuet, Christophe Broca, Safia Costes, +3

Endocrinology

Cell DifferentiationInsulin GranulesCellular PhysiologyInsulin SignalingSignaling Pathway +18

Genetic Studies of the Sulfonylurea Receptor Gene Locus in NIDDM and in Morbid Obesity Among French Caucasians

El Habib Hani, Karine Clément, Gilberto Velho, +11

Diabetes

Glucagon Promotes cAMP-response Element-binding Protein Phosphorylation via Activation of ERK1/2 in MIN6 Cell Line and Isolated Islets of Langerhans

Stéphane Dalle, Christine Longuet, Safia Costes, +5

Journal of Biological Chemistry

Genetics of NIDDM in France: Studies With 19 Candidate Genes in Affected Sib Pairs

Nathalie Vionnet, El Habib Hani, Suzanne Lesage, +11

Diabetes