Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma

Frederick L. Locke, David B. Miklos, Caron A. Jacobson, +28

New England Journal of Medicine

Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma

Jason R. Westin, Olalekan O. Oluwole, Marie José Kersten, +27

New England Journal of Medicine

PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

Fara Brasó‐Maristany, Simone Filosto, Steven Catchpole, +25

Nature Medicine

Breast OncologyOncologyMedicineTumor GrowthPim1 Kinase +10

Impact of tumor microenvironment on efficacy of anti-CD19 CAR T cell therapy or chemotherapy and transplant in large B cell lymphoma

Frederick L. Locke, Simone Filosto, Justin Chou, +22

Nature Medicine

Neutral Sphingomyelinase 2

Simone Filosto, Sianna Castillo, Aaron Danielson, +7

American Journal of Respiratory Cell and Molecular Biology

Inflammatory Lung DiseaseLung InflammationCell DeathMolecular BiologyPulmonary Alveolar Proteinosis +19

Cigarette Smoke Induces Aberrant EGF Receptor Activation That Mediates Lung Cancer Development and Resistance to Tyrosine Kinase Inhibitors

Simone Filosto, Cathleen R. Becker, Tzipora Goldkorn

Molecular Cancer Therapeutics

Kinase InhibitorsCigarette SmokeTumor BiologyTobacco ControlNicotine +15

EGF Receptor Exposed to Oxidative Stress Acquires Abnormal Phosphorylation and Aberrant Activated Conformation That Impairs Canonical Dimerization

Simone Filosto, Elaine M. Khan, Emiliana Tognon, +4

PLoS ONE

Molecular BiologyChemical BiologyRedox BiologyOxidative StressSignaling Pathway +18

Neutral Sphingomyelinase 2 (nSMase2) Is a Phosphoprotein Regulated by Calcineurin (PP2B)

Simone Filosto, William Fry, Anne A. Knowlton, +1

Journal of Biological Chemistry

Cadmium induces an apoptotic response in sea urchin embryos

Maria Agnello, Simone Filosto, Rosaria Scudiero, +2

Cell Stress and Chaperones

BiologyBioactive MetalSea Urchin EmbryosTrace MetalToxicology +4

Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro

Simone Filosto, Maria Carmela Roccheri, Rosa Bonaventura, +1

Cell Biology and Toxicology

BiologyEcotoxicityDevelopmental BiologyBioactive MetalParacentrotus Lividus Larvae +8