Makram Essafi

An Isoleucine-based Allosteric Switch Controls Affinity and Shape Shifting in Integrin CD11b A-domain

Jian-Ping Xiong, Rui Li, Makram Essafi et al. · Journal of Biological Chemistry · 2000 · 144 citations · Full text

Engineering, Protein Assembly, Integrin Cd11b A-domain +16

Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 Phenotype

Amira Refai, Sami Gritli, Mohamed‐Ridha Barbouche et al. · Frontiers in Cellular and Infection Microbiology · 2018 · 136 citations · Full text

The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

Ichrak Riahi-Chebbi, Soumaya Souid, Houcemeddine Othman et al. · Scientific Reports · 2019 · 125 citations · Full text

Chemoprevention Strategy, Tumor Biology, Polyphenolics +16

Polycystin-1 Activates and Stabilizes the Polycystin-2 Channel

Gang Xu, Silvia González‐Perrett, Makram Essafi et al. · Journal of Biological Chemistry · 2003 · 101 citations · Full text

Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition

Khadija Essafi‐Benkhadir, Amira Refai, Ichrak Riahi et al. · Biochemical and Biophysical Research Communications · 2012 · 96 citations

Inflammation, Molecular Pharmacology, Medicine +11