Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism

Houcemeddine Othman, Zied Bouslama, Jean‐Tristan Brandenburg, +5

Biochemical and Biophysical Research Communications

Receptor PolymorphismImmunologyReceptor (Biochemistry)Molecular BiologyHot-spot Analysis +2

The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

Ichrak Riahi-Chebbi, Soumaya Souid, Houcemeddine Othman, +6

Scientific Reports

Chemoprevention StrategyTumor BiologyPolyphenolicsPhenolic Compound KaempferolDrug Resistance +14

PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells

Maram Morjen, Olfa Kallech-Ziri, Amine Bazaa, +9

Matrix Biology

Neuro-oncologyDrug TargetingImpairs MotilityGliomaMedicine +7

Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Ons Zakraoui, Cezary Marcinkiewicz, Zohra Aloui, +9

Molecular Carcinogenesis

Heterodimeric DisintegrinChemoprevention StrategyApoptosisImmunologyCell Death +17

Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells

Chedli Ellijimi, M. Ben Hammouda, Houcemeddine Othman, +9

Biomedicine & Pharmacotherapy

Maxima Mucus ExhibitsPhotocarcinogenesisMelanomaMelanoma CellsAntitumoral Effects +7

Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

D. Aissaoui, Saoussen Mlayah‐Bellalouna, Jed Jebali, +9

International Journal of Biological Macromolecules

Molecular PhysiologySignal TransductionSignaling PathwayMedicineCell Interaction +9

Two distinct conformational states of <i>Mycobacterium tuberculosis</i> virulent factor early secreted antigenic target 6 <scp>kD</scp>a are behind the discrepancy around its biological functions

Amira Refai, Meriam Haoues, Houcemeddine Othman, +6

FEBS Journal

In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect

S Boubaker, Houcemeddine Othman, Rabeb Touati, +6

BMC Bioinformatics

Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin

M. Ben Hammouda, Ichrak Riahi-Chebbi, Soumaya Souid, +10

Biochimica et Biophysica Acta (BBA) - General Subjects

Tumor BiologyProliferation MigrationMedicineMacrovipera Lebetina VenomImmunology +5

Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects

Yosr Hamdi, Lyndon Zass, Houcemeddine Othman, +19

OMICS A Journal of Integrative Biology